Gimp has so many usability issues and GIMP team is going to address some of them in 2.6 version.
Gimp 2.6 will have only one menu bar
One of the primary usability issue that confuses newbies is two global menu bars (One in tools palette & second one in image window). Now Gimp is going to get rid of tools palette menu bar and display only one menu bar in image window. So image window is always open and its background defaults to gray if there is no image in use.
Current implementation of GEGL is going to pave a way for future CYMK support. CYMK is important for professionals to accurately print images with exact colors. This is not much important for web developers & home users and they can live without CYMK.
Another much awaited GUI improvement. This is really useful to people who switch between different tool dialogs.
There are many more improvements to Gimp 2.6 and lets see whether its going to be interesting to use.